Dr Cynthia Bonhof

Bio

In my doctoral research I investigated the effect of chemotherapy-induced peripheral neuropathy (CIPN) on the lives of patients with cancer. In 2021, this resulted in a dissertation, which showed that cancer patients with CIPN generally have a worse health-related quality of life, including more anxiety and depressive symptoms, fatigue, and worse sleep quality. As a postdoctoral researcher I continue my research on CIPN among (colorectal) cancer patients, but also investigate other important topics such as the effect of different surgical procedures on patients’ quality of life. Also, as we do not only collect questionnaire data, but also data by means of blood samples, we will also focus on the role of cancer(treatment) on biological markers such as inflammatory markers and leukocyte telomere length, and their association with patient-reported outcomes.

Recent publications

1. Perioperative systemic therapy versus cytoreductive surgery and HIPEC…

   Dutch Peritoneal Oncology Group and the Dutch Colorectal Cancer Group (2023). Perioperative systemic therapy versus cytoreductive surgery and HIPEC alone for resectable colorectal peritoneal metastases: Patient reported outcomes of a randomized phase II trial. Annals of Surgical Oncology, 30(5), 2678-2688.

2. The impact of cytoreductive surgery and hyperthermic intraperitoneal …

   Bakkers, C., van de Vlasakker, V. C. J., Rovers, K. P. B., Lurvink, R. J., Nienhuijs, S. W., Burger, J. W. A., Creemers, G. M., Bonhof, C. S., Mols, F., & de Hingh, I. H. J. T. (2023). The impact of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS-HIPEC) versus conventional surgery on patient-reported Outcomes: A comparative cohort study between the CAIRO6 trial and the PROCORE study. Cancers, 15(3), Article 788.

3. Association between peripheral neuropathy and sleep quality among col…

   Bonhof, C., van de Poll-Franse, L. V., de Hingh, I. H. J. T., Nefs, G. M., Vreugdenhil, G., & Mols, F. (2023). Association between peripheral neuropathy and sleep quality among colorectal cancer patients from diagnosis until 2-year follow-up: Results from the PROFILES registry. Journal of Cancer Survivorship, 17(3), 894-905.

4. Colorectal cancer and cardiovascular disease - Double the burden when…

   Bonhof, C., Mols, F., Widdershoven, J., & Schoormans, D. (2023). Colorectal cancer and cardiovascular disease: Double the burden when it comes to your health-related quality of life? Acta Oncologica, 62(7), 737-743.

5. Mindfulness is associated with severity of peripheral neuropathy and …

   Bonhof, C. S., van de Poll-Franse, L. V., de Hingh, I. H., Vreugdenhil, G., & Mols, F. (2022). Mindfulness is associated with severity of peripheral neuropathy and related patient-reported outcomes among colorectal cancer patients. Supportive Care in Cancer, 30(11), 9517-9526.